Internal Medicine Residency

University of Pittsburgh

Training Program: International Scholars Program

Our Residents

Check out the Clinical Scientist Track Residents

Entering 2011:

Tinashe Gede picture Tinashe Gede Primary Research Area of Interest: Inflammatory Bowel Disease
Primary Clinical Area of Interest: Gastroenterology
ISP Research Project Title:
Mentor for ISP Project: Dr David Binion
Sangeeta Goswami picture Sangeeta Goswami Primary Research Area of Interest: Pulmonary Immunology
Primary Clinical Area of Interest: Pulmonary, Oncology
ISP Research Project Title: Role of inflammatory milieu in COPD and Lung Cancer pathogenesis
Mentor for ISP Project: Steven Shapiro
Publications:
  • Goswami S, Angkasekwinai P, Shan M, Greenlee K.J, Barranco W.T, Polikepahad S, Seryshev A, A, Sur S, Woodruff C, Dong C, Corry D.B, Kheradmand F. Divergent Roles of Airway Epithelial MMP7 and ATRA in Experimental Asthma. Nature Immunology, 2009, 496 - 503.
  • Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, Goodnight-White S, Green L,Hacken-Bitar J, Huh J, Bakaeen F, Coxson HO, Cogswell S, Storness-Bliss C, Corry DB, Kheradmand F. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nature Medicine, 2007 May;13(5):567-9.
  • Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH. Identification of P311 as a potential gene regulating alveolar generation. Am J Respir Cell Mol Biol. 2006 Jul;35(1):48-54.
  • Sharma M, Batra J, Mabalirajan U, Goswami S, Ganguly D, Lahkar B, Bhatia NK, Kumar A, Ghosh B. Suggestive evidence of association of C-159T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations. Immunogenetics. 2004 Oct;56(7):544-7.
Abstracts
  • Sangeeta Goswami, Young-Ho Ahn, Wei Lin, Melanie Mediavilla-Varela, Xuejun Zhang, Erez Baruch, David W. Dwyer, Christin Ungewiss, Mayuri P. Patel, Scott Antonia, F. Xiao-Feng Qin, Jonathan M. Kurie. miR-200 suppression in tumor cells promotes metastasis by triggering intra-tumoral CD8+ T cell anergy. IDIBELL Cancer Conference on Metastasis and Angiogenesis, 2011.
  • Sangeeta Goswami, Wei Lin, David Dwyer, Xiao-Feng Qin, Jonathan M. Kurie. Role of Inflammatory Cells in Lung Cancer Metastasis. Keystone Symposium, 2010.
  • Goswami S, Angkasekwinai P, Shan M, Greenlee K.J, Barranco W.T, Polikepahad S, Seryshev A, A, Sur S, Woodruff C, Dong C, Corry D.B, Kheradmand F. Divergent Roles of Airway Epithelial MMP7 and ATRA in Experimental Asthma. The Journal of Immunology. 2009, 182, 140.5
  • Goswami, S., Barranco, W., Greenlee, K. J., Seryshev, A. B., Corry, D. B. and Kheradmand, F. (2008). "Role of matrix-metalloprotease-7 in a model of experimental asthma". FASEB Journal. 22, 671.3.
  • Goswami, S., Barranco. W., Lee. S.L., Grudo, A., Corry, D. B. and Kheradmand, F (2007). "An autoimmune basis in the disease pathogenesis of COPD/Emphysema". The Journal of Immunology. 178: 130.41.
  • Goswami, S., Barranco. W., Lee. S.L., Grudo, A., Corry, D. B. and Kheradmand, F (2007). "An autoimmune basis in the disease pathogenesis of COPD/Emphysema". National Student Research Forum (NSRF), Galveston, TX.
  • Lee. S.L., Goswami, S., Grumelli. S, Corry, D. B. and Kheradmand, F (2006). "Elastin derived peptide mediate autoimmune basis for smoking-induced emphysema in human", American Association of Immunologists (AAI), Boston, MA
Charbel C Khoury picture Charbel C Khoury Primary Research Area of Interest: Chronic Kidney Disease, with special interest in Diabetic renal disease
Primary Clinical Area of Interest: Nephrology
ISP Research Project Title:
Mentor for ISP Project: Mark Unruh
Publications:
  • Brosius FC, Khoury CC, Buller CL, Chen S.. Abnormalities in signaling pathways in diabetic nephropathy.. Expert Rev Endocrinol Metab. 2010 Jan; 5(1): 51-64. Cited in PubMed; PMID: 20224802.
  • Lee EY, Chung CH, Khoury CC, Yeo TK, Pyagay PE, Wang A, Chen S.. The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability.. Am J Physiol Renal Physiol. 2009 Jul; 297(1): F85-94. Cited in PubMed; PMID: 19420107.
  • Khoury, CC., Ziyadeh, FN. Growth Factors in Diabetes. In Prabakhar, S. (Ed.), Advances in the Pathogenesis of Diabetic Nephropathy. 2011 USA. Novascience.
  • Khoury, CC., Ziyadeh, FN. Angiogenic Factors. Contrib Nephrol. 2011;170:83-92. Cited in Pubmed; PMID: 21659761
Florian B Mayr picture Florian B Mayr Primary Research Area of Interest: Severe sepsis, racial disparities and long term outcomes after severe sepsis
Primary Clinical Area of Interest: Critical care medicine
ISP Research Project Title: Understanding racial differences in severe sepsis
Mentor for ISP Project: Sachin Yende
Publications:
  • Mayr FB, Yende S, Linde-Zwirble WT, Peck-Palmer OM, Barnato AE, Weissfeld LA, Angus DC. Infection Rate and Acute Organ Dysfunction Risk as Explanations for Racial Differences in Severe Sepsis. JAMA. 2010; 303:2495-2503.
  • Mayr FB, Knoebl P, Jilma B, Siller-Matula J, Wagner P, Schaub RG, Gilbert JC, Jilma-Stohlawetz P. The Aptamer ARC1779 blocks VWF dependent platelet function in patients with thrombotic thrombocytopenic purpura (TTP) ex vivo. Transfusion 2010;50:1079-1087.
  • Mayr FB, Yende S, D'Angelo G, Kellum JA, Weissfeld L, Yealy D, Barnato AE, Reade MC, Milbrandt EB, Angus DC. Do hospitals provide different quality of care to blacks for pneumonia? Crit Care Med 2010;38:759-65.
  • Spiel AO, Mayr FB, Ladani N, Wagner PG, Schaub RG, Gilbert JC, Jilma B. The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor mediated ex vivo platelet function in acute myocardial infarction. Platelets 2009;20:334-40.
  • Mayr FB, Spiel AO, Leitner JM, Firbas C, Schnee J, Hilbert J, Derendorf W, Jilma B. Influence of the Duffy antigen on pharmacokinetics and pharmacodynamics of monocyte chemoattractant protein (MCP-1) in humans. Int J Immunopathol Pharmacol 2009; 22(3):615-25.
  • Spiel AO, Kliegel A, Janata A, Uray T, Mayr FB, Laggner AN, Jilma B, Sterz F. Hemostasis in Cardiac Arrest Patients Treated with Mild Hypothermia Initiated by Cold Fluids. Resuscitation 2009;80:762-5.
  • Mayr FB, Spiel AO, Leitner JM, Firbas C, Jilma-Stohlawetz P, Jen-Yeah C, Key NS, Jilma B. Racial Differences in endotoxin induced tissue factor-triggered coagulation; J Thromb Haemost 2009; 7:634-40.
  • Spiel AO, Frossard M, Mayr FB, Kliegel A, Janata A, Uray T, Wandaller C, Sterz F, Jilma B. Pronounced platelet hyperfunction in patients with cardiac arrest achieving restoration of spontaneous circulation; Crit Care Med 2009; 37:975-9.
  • Reade MC, Yende S, D'Angelo G, Kong L, Kellum JA, Milbrandt EB, Dooley C, Mayr FB, Barnato AE, Weissfeld L, Angus DC. Differences in immune response may explain lower survival among older men with pneumonia. Crit Care Med 2009; 37:1655-62.
  • Leitner JM, Mayr FB, Spiel AO, Firbas C, Savulsky C, Mis R, Corrado ME, Jilma B. The pharmacokinetics and pharmacodynamics of a new sustained-release leuprolide acetate depot compared to market references. Int J Clin Pharmacol Ther 2008; 46(8):407-14.
  • Spiel AO, Mayr FB, Leitner JM, Firbas C, Sieghart W, Jilma B. Simvastatin and rosuvastatin mobilize Endothelial Progenitor Cells but do not prevent their acute decrease during systemic inflammation. Thromb Res 2008;123(1):108-13.
  • Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B. The Duffy Antigen modifies the Inflammatory Response in Human Endotoxemia; Crit Care Med 2008; 36(1):159-65.
  • Mayr FB, Firbas C, Leitner JM, Spiel AO, Reiter R, Jilma B. Effects of the pan-selectin antagonist Bimosiamose (TBC1269) in experimental human endotoxemia. Shock 2008; 29(4):475-82.
  • Mayr FB, Spiel AO, Leitner JM, Firbas C, Sieghart W, Jilma B. Effects of Low Dose Endotoxemia on Endothelial Progenitor Cells in Humans. Atherosclerosis 2007; 195(1):e202-6.
  • Leitner JM, Jilma B, Mayr FB, Cardona F, Spiel AO, Firbas C, Rathgen K, Stähle H, Schühly U, Graefe-Mody EU. Pharmacokinetics and pharmacodynamics of the dual FII/FX inhibitor BIBT 986 in endotoxin induced coagulation. Clin Pharmacol Ther 2007; 81(6):858-66.
  • Leitner JM, Mayr FB, Firbas C, Spiel A, Steinlechner B, Novellini R, Jilma B. Reparixin, a specific interleukin-8 inhibitor, has no effects on inflammation during endotoxemia. Int J Immunopathol Pharmacol 2007; 20(1):25-36.
  • Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma B. Ethnic differences in plasma levels of
  • Interleukin-8 and granulocyte colony stimulating factor levels (G-CSF). Transl Res. 2007; 149:10-14.
  • Mayr FB, Jilma B. Coagulation Interventions in Experimental Human Endotoxemia. Transl Res. 2006; 148: 263-71.
  • Mayr FB, Jilma B. Current Developments in Anti-Platelet Therapy. Wien Med Wochenschr 2006. 156: 472-80.
  • Boos CJ, Mayr FB, Lip GY, Jilma B. Endotoxemia enhances circulating endothelial cells in humans. J Thromb Haemost 2006; 4: 2547-52.
  • Spiel AO, Mayr FB, Firbas C, Quehenberger P, Jilma B. Validation of rotation thrombelastography in a model of systemic activation of fibrinolysis and coagulation in humans. J Thromb Haemost 2006; 4: 411-16.
  • Leitner JM, Firbas C, Mayr FB, Reiter RA, Steinlechner B, Jilma B. Recombinant human antithrombin inhibits thrombin formation and interleukin-6 release in human endotoxemia. Clin Pharmacol Ther 2006; 79: 23-34.
  • Spiel AO, Firbas C, Mayr FB, Leitner JM, Schmidt B, Knobl P, Varadi K, Jilma B. The effects of supranormal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia. Thromb Haemost 2005; 94: 1148-55.
  • Mayr FB, Spiel A, Leitner JM, Marsik C, Gehrmann P, Ullrich R, Wagner O, Jilma B. Effects of carbon monoxide inhalation during experimental endotoxemia in humans. Am. J. Respir. Crit. Care Med. 2005; 15; 171:354-60.
  • Marsik C, Mayr F, Cardona F, Schaller G, Wagner OF, Jilma B. Endotoxin down-modulates P-selectin glycoprotein ligand-1 (PSGL-1, CD162) on neutrophils in humans. J Clin Immunol 2004; 24:62-5.
  • Endler G, Marsik C, Joukhadar C, Marculescu R, Mayr F, Mannhalter C, Wagner OF, Jilma B. The Interleukin 6 G(-174)C promoter polymorphism does not determine plasma interleukin-6 levels in experimental endotoxemia in man. Clin Chem 2004; 50:195-200.
  • Marsik C, Halama T, Cardona F, Wlassits W, Mayr F, Pleiner J, Jilma B. Regulation of Fas (APO-1, CD95) and Fas Ligand expression in leukocytes during systemic inflammation in humans. Shock 2003; 20:493-6.
  • Reiter RA, Derhaschnig U, Spiel A, Keen P, Cardona F, Mayr F, Jilma B. Regulation of protease-activated receptor 1 (PAR1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans. Thromb Haemost 2003; 90:898-903.
  • Reiter RA, Mayr F, Blazicek H, Galehr E, Jilma-Stohlawetz P, Domanovits H, Jilma B. Desmopressin antagonizes the in vitro platelet dysfunction induced by GP IIb/IIIa inhibitors and aspirin. Blood 2003; 102:4594-9.
  • Marsik C, Mayr F, Cardona F, Derhaschnig U, Wagner OF, Jilma B. Endotoxaemia modulates Toll-like receptors on leukocytes in humans. Br J Haematol 2003; 121:653-6.
  • Jilma B, Marsik C, Mayr F, Graninger MT, Taylor FB, Jr., Ribel MC, Erhardtsen E, Handler S, Eichler HG. Pharmacodynamics of active site inhibited factor VIIa (ASIS, FFR-rFVIIa) in endotoxin induced coagulation in humans. Clin Pharmacol Ther 2002; 72:403-10.
  • Yende S, D'Angelo G, Mayr FB, Kellum JA, Kaynar AM, Kaikobad I, Angus DC. Persistent prothrombotic state at hospital discharge after pneumonia increases risk of cardiovascular deaths. Circulation; submitted.
  • Spiel AO, Mayr FB. NO-synthase inhibition in sepsis. Thromb Haemost. 2006; 95:591-2.
  • Mayr FB, Bilban M, Jilma B. "Low-level" carbon monoxide administration may carry risk. Am J Respir Crit Care Med. 2005; 172:784-5.
  • Mayr FB, Yende S, Angus DC. Racial disparities in infection and sepsis - does biology matter? In: Vincent J-L (ed), 2008 Yearbook of Intensive Care and Emergency Medicine, Springer-Verlag, Berlin.
  • Nguyen YLC, Mayr FB, Angus DC. Intensive care use and end-of-life decision-making -An American and European perspective. In: Vincent J-L (ed), 2010 Yearbook of Intensive Care and Emergency Medicine, Springer-Verlag, Berlin.
Presentations at major scientific meetings:
  • Mayr FB, Yende S, Angus DC, Linde-Zwirble WT. Understanding Racial Differences in Severe Sepsis Incidence. Intensive Care Med 2009; 35(Suppl1):P87.
  • Poster presentation at the 22nd Annual Congress of the European-Society-of-Intensive-Care-Medicine, Vienna, Austria.
  • Mayr FB, Yende S, Kellum JA, D'Angelo G and Angus DC. Prothrombotic state at hospital discharge increases 1-year mortality in pneumonia and sepsis survivors. Critical Care 2009; 13(Suppl 1):P444.
  • Poster presentation at the 29th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium.
  • Mayr FB, Yende S, Milbrandt EB, Kellum JA, Reade MC, Angus DC. Racial disparities in quality of care in community-acquired pneumonia. Critical Care 2008; 12(Suppl 2):P424.
  • Poster presentation at the 28th International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium.
  • Mayr FB, Spiel AO, Leitner JM, Firbas C, Jilma B. The Duffy antigen modifies the procoagulant response in human endotoxemia. Crit Care Med 2007; 35(Suppl):A2.
  • Oral presentation at the 37th Critical Care Congress of the Society-of-Critical-Care-Medicine, Honolulu, USA.
  • Mayr FB, Jilma-Stohlawetz P, Firbas C, Leitner JM, Spiel AO, Jilma B. Functional role of the chemokine binding duffy antigen receptor complex (DARC) in human inflammation in vivo. Blood 2006; 108(Suppl1):10A.
  • Oral presentation at the 48th Annual Meeting of the American-Society-of-Hematology, Orlando, USA.
Gurprataap S Sandhu picture Gurprataap S Sandhu Primary Research Area of Interest: Oncology Basic Science
Primary Clinical Area of Interest: Hematology Oncology
ISP Research Project Title:
Mentor for ISP Project: Michael E Kirkwood
Lin Shen picture Lin Shen Primary Research Area of Interest: Immunology, Pharmacology
Primary Clinical Area of Interest: Infectious disease, Rheumatology, Hematology/Oncology
ISP Research Project Title:
Mentor for ISP Project: Dr. Fadi Lakkis
Publications:
  • Jilek BL, Zarr M, Sampah ME, Rabi SA, Bullen CK, Lai J, Shen L, Siliciano RF. A quantitative basis for antiretroviral therapy for HIV-1 infection. Nature Medicine 18(3):446-51 (2012).
  • Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. A critical subset model provides a conceptual basis for high antiviral activity of major HIV-1 drugs. Science Translational Medicine 3(91):91ra63 (2011).
  • Sampah ME, Shen L, Jilek BL, Siliciano RF. Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance. Proceedings of the National Academy of Sciences, USA 108(18):7613-8 (2011).
  • McMahon MA, Parsons TL, Shen L, Siliciano JD, Siliciano RF. Consistent inhibition of HIV-1 replication by acyclovir in CD4+ T cells without detection of human herpes viruses. Journal of Virology. 85(9):4618-22 (2011).
  • Rabi SA, O'Connell KA, Nikolaeva D, Bailey JR, Jilek BL, Shen L, Page K, Siliciano RF, Blankson JN. Unstimulated primary CD4+ T cells from HIV-1 positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. Journal of Virology. 85(2): 979-86 (2011).
  • Bellows ML, Taylor MS, Cole PA, Shen L, Siliciano RF, Fung HK, Floudas CA. Discovery of entry inhibitors for HIV-1 via a new de novo protein design framework. Biophysical Journal 99(10):3445-53 (2010).
  • Shen L, Siliciano RF. Achieving a quantitative understanding of antiretroviral drug efficacy. Clinical Infectious Diseases 51(9):1105-6 (2010).
  • Shen L, Rabi SA, Siliciano RF. A novel method for determining the inhibitory potential of anti-HIV drugs. Trends in Pharmacological Sciences 30(12):610-6 (2009).
  • McMahon MA, Shen L, Siliciano RF. New approaches for quantitating the inhibition of HIV-1 replication by antiviral drugs in vitro and in vivo. Current Opinion in Infectious Diseases 22(6): 574-82 (2009).
  • Yang H-C, Shen L, Siliciano RF, Pomerantz JL. Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation. Proceedings of the National Academy of Sciences, USA 106(15): 6321-6 (2009).
  • Shen L, Peterson S, Sedaghat AR, McMahon MA, Callender M, Zhang H, Zhou Y, Pitt E, Anderson KS, Acosta EP, Siliciano RF. Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs. Nature Medicine 14(7): 762-766 (2008).
  • Shen L, Siliciano RF. Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection. Journal of Allergy and Clinical Immunology 122(1): 22-28 (2008).
  • Zhou Y, Shen L, Yang HC, Siliciano RF. Preferential cytolysis of peripheral memory CD4+ T cells by in vitro X4-tropic human immunodeficiency virus type 1 infection before the completion of reverse transcription. Journal of Virology 82(18): 9154-9163 (2008).
  • Sedaghat AR, Dinoso JB, Shen L, Wilke CO, Siliciano RF. Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle. Proceedings of the National Academy of Sciences, USA 105: 4832-4837 (2008).
  • McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio TL. The HBV drug entecavir - effects on HIV-1 replication and resistance. New England Journal of Medicine 356: 2614-2621 (2007).


Entering 2010:

Sunil Agarwal picture Sunil Agarwal Primary Research Area of Interest: Cardiovascular epidemiology, electrophysiology, and public health practice.
Primary Clinical Area of Interest: Cardiology
ISP Research Project Title: Use of Anti-Coagulant/Anti-Platelet Therapy for Atrial Fibrillation in the US Outpatient Settings: Is it Guided by Appropriate Risk Stratification?
Mentor for ISP Project: Samir Saba, MD.
Publications:
  • Alonso A, Agarwal SK, Soliman EZ, Ambrose M, Chamberlain AM, Prineas RJ, Folsom AR. Incidence of atrial fibrillation in whites and African Americans: the Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J. 2009;158(1):111-7.
  • Agarwal SK, Heiss G, Rautaharju P, Shahar E, Massing M, Simpson RJ. Ventricular premature complexes and risk of incident stroke: an Atherosclerosis Risk in Communities Study. Stroke. 2010;41(4):588-93.
  • Chamberlain AM, Agarwal SK, Ambrose M, Folsom AR, Soliman EZ, Alonso A. Metabolic syndrome and incidence of atrial fibrillation among blacks and whites in the Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J. 2010;159(5):850-6.
  • Goel R, Misra A, Agarwal SK, Vikram N. Correlates of hypertension among urban Asian Indian adolescents. Arch Dis Child. 2010;95(12):992-7.
  • Le Groupe Pulmonaria, Quanjer PH, Enright PL, Stocks J, …Agarwal SK, et al. [Open letter to the members of the GOLD committee]. Rev Mal Respir. 2010;27(9):1003-7.
  • Chamberlain AM, Agarwal SK, Folsom AR, Soliman EZ, Chambless LE, Crow R, Ambrose M, Alonso A. A clinical risk score for atrial fibrillation in a biracial prospective cohort (from the Atherosclerosis Risk in Communities [ARIC] study). Am J Cardiol. 2011;107(1):85-91.
  • Huxley RR, Lopez FL, Folsom AR, Agarwal SK, Loehr LR, Soliman EZ, Maclehose R, Konety S, Alonso A. Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation. 2011;123(14):1501-8.
  • Agarwal SK, Avery CL, Ballantyne CM, Catellier D, Nambi V, Saunders J, Sharrett AR, Coresh J, Heiss G, Hoogeveen RC. Sources of variability in measurements of cardiac troponin T in a community-based sample: the ARIC Study. Clin Chem. In press.
  • Alonso A, Lopez FL, Agarwal SK, Loehr L, Soliman EZ, Maclehose R, Konety S, Folsom AR. Chronic kidney disease is associated with the incidence of atrial fibrillation: the ARIC Study. Circulation. In press.
  • Alonso A, Tang W, Agarwal SK, Soliman EZ, Chamberlain AM, Folsom AR. Hemostatic markers are associated with the risk and prognosis of atrial fibrillation: the ARIC Study. Int J Cardiol. In press.
  • Chamberlain AM, Agarwal SK, Folsom AR, Duval S, Soliman EZ, Ambrose M, Eberly LE, Alonso A. Smoking and incidence of atrial fibrillation: results from the Atherosclerosis Risk in Communities (ARIC) Study. Heart Rhythm. In press.
  • Yaemsiri S, Slining MM, Agarwal SK. Perceived weight status, overweight diagnosis, and weight control among US adults: the NHANES 2003-2008 Study. Int J Obes (Lond). In press.
  • 1. Agarwal SK, Simpson RJ, Rautaharju R, Alonso A, Shahar E, Massing M, Saba S, Heiss G. Relation of Ventricular Premature Complexes to Heart Failure (From the Atherosclerosis Risk in Communities [ARIC] Study). – American Journal of Cardiology - In press
  • Huxley RR, Alonso A, Lopez FL, Filion KB, Agarwal SK, Loehr LR, Soliman EZ, Pankow JS, Selvin E. Type 2 diabetes, glucose homeostasis and incident atrial fibrillation: the Atherosclerosis Risk in Communities Study – Heart. 2011 Sep 19. [Epub ahead of print]
  • Tamariz L, Agarwal S, Soliman EZ, Chamberlain AM, Prineas R, Folsom AR, Ambrose M, Alonso A. Association of Serum Uric Acid With Incident Atrial Fibrillation (from the Atherosclerosis Risk in Communities [ARIC] Study). Am J Cardiol. 2011 Aug 17. [Epub ahead of print]
  • Alonso A, Lopez FL, Matsushita K, Loehr LR, Agarwal SK, Chen LY, Soliman EZ, Astor BC, Coresh J. Chronic Kidney Disease Is Associated With the Incidence of Atrial Fibrillation: The Atherosclerosis
  • Risk in Communities (ARIC) Study, Circulation. 2011 Jun 6. [Epub ahead of print]
  • Bekwelem W, Lutsey PL, Loehr LR, Agarwal SK, Astor BC, Guild C, Ballantyne CM, Folsom AR:White blood cell count, C-reactive protein and incident heart failure in the At
Sebhat Erqou picture Sebhat Erqou Primary Research Area of Interest: Infectious diseases, cardiovascular diseases, and interdisciplinary research.
Primary Clinical Area of Interest: Infectious diseases and cardiology.
ISP Research Project Title: Liver enzymes and risk of cardiovascular disease.
Mentor for ISP Project: Adeel Butt, MD.
Publications:
  • Emerging Risk Factors Collaboration, Danesh J, Erqou S, Walker M, Thompson SG, Tipping R, Ford C, Pressel S, Walldius G, Jungner I, Folsom AR, Chambless LE, Knuiman M, et al. The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol. 2007;22(12):839-69.
  • Erqou SA, Teferra E, Mulu A, Kassu A. A case of shigellosis with intractable septic shock and convulsions. Jpn J Infect Dis. 2007;60(5):314-6.
  • Bennet A, Di Angelantonio E, Erqou S, Eiriksdottir G, Sigurdsson G, Woodward M, Rumley A, Lowe GD, Danesh J, Gudnason V. Lipoprotein(a) levels and risk of future coronary heart disease: large-scale prospective data. Arch Intern Med. 2008;168(6):598-608.
  • Erqou S, Kebede Y, Mulu A. Increased resistance of Streptococcus pneumoniae isolates to antimicrobial drugs, at a referral hospital in northwest Ethiopia. Trop Doct. 2008;38(2):110-2.
  • Thompson A, Di Angelantonio E, Sarwar N, Erqou S, Saleheen D, Dullaart RP, Keavney B, Ye Z, Danesh J. Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk. JAMA. 2008;299(23):2777-88.
  • Danesh J, Erqou S. Risk factors: Lipoprotein(a) and coronary disease-moving closer to causality. Nat Rev Cardiol. 2009;6(9):565-7.
  • Emerging Risk Factors Collaboration, Erqou S, Kaptoge S, Perry PL, Di Angelantonio E, Thompson A, White IR, Marcovina SM, Collins R, Thompson SG, Danesh J. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA. 2009;302(4):412-23.
  • Lee CC, Adler AI, Sandhu MS, Sharp SJ, Forouhi NG, Erqou S, Luben R, Bingham S, Khaw KT, Wareham NJ. Association of C-reactive protein with type 2 diabetes: prospective analysis and meta-analysis. Diabetologia. 2009;52(6):1040-7.
  • Ray KK, Seshasai SR, Wijesuriya S, Sivakumaran R, Nethercott S, Preiss D, Erqou S, Sattar N. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials. Lancet. 2009;373(9677):1765-72.
  • Adler AI, Erqou S, Lima TA, Robinson AH. Association between glycated haemoglobin and the risk of lower extremity amputation in patients with diabetes mellitus: review and meta-analysis. Diabetologia. 2010;53(5):840-9.
  • Erqou S, Thompson A, Di Angelantonio E, Saleheen D, Kaptoge S, Marcovina S, Danesh J. Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants. J Am Coll Cardiol. 2010;55(19):2160-7.
  • Ray KK, Seshasai SR, Erqou S, Sever P, Jukema JW, Ford I, Sattar N. Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65,229 participants. Arch Intern Med. 2010;170(12):1024-31.
  • Sarpatwari A, Provan D, Erqou S, Sobnack R, David Tai FW, Newland AC. Autologous 111 In-labelled platelet sequestration studies in patients with primary immune thrombocytopenia (ITP) prior to splenectomy: a report from the United Kingdom ITP Registry. Br J Haematol. 2010;151(5):477-87.
  • Sarpatwari A, Watson S, Erqou S, Anderson H, Grainger J, Higgins JP, Newland AC. Health-related lifestyle in adults and children with primary immune thrombocytopenia (ITP). Br J Haematol. 2010;151(2):189-91.
Pashtoon Kasi picture Pashtoon Kasi Primary Research Area of Interest: Hematology Oncology/Medical Education
Primary Clinical Area of Interest: Hematology Oncology/Medical Education
ISP Research Project Title:
  • Reliability and Exploratory Factor Analysis of Brief COPE in residents in internal medicine.
  • Association of Burnout with coping strategies in residents in internal medicine.
  • Role of Chest Xray and LDH in the surveillance for patients with high-risk melanoma
  • Molecular Profiling in Melanoma.
  • Association of hepatitis C virus with thromboembolim
Mentor for ISP Project:
  • Dr. Asher Tulsky
  • Dr. Hussein Tawbi
  • Dr. Adeel Butt
Publications:
  • Kasi PM, Pal I. Using choriocarcinoma to cause remission of other tumors: A novel approach to kill tumors. Med Hypotheses. 2007;68(3):717.
  • Kasi PM, Khawar T, Khan FH, Kiani J, Khan UZ et al. Studying the association between postgraduate trainee's work hous, stress and the use of maladaptive coping strategies. J Ayub Med Coll Abbottabad 2007; 19(3), 37-41.
  • Kasi PM, Gilani AI, Zaidi AH. Improvement of water and sanitation for developing countries. Lancet. 2004 Mar 13; 363(9412):899-900.
  • Kasi PM, Gilani AI. Trachoma still ignored in developing countries. Lancet. 2004 May 22; 363(9422):1736.
  • Janjua NZ, Kasi PM, Nawaz H, Farooqui SZ, Khuwaja UB et al. Acute health effects of the Tasman Spirit oil spill on residents of Karachi, Pakistan. BMC Public Health. 2006; 6(1):84
  • Kasi PM, Gilani AI, Ahmad K, Janjua NZ. Blinding trachoma: a disease of poverty. PLoS Med. 2004 Nov;1(2):e44.
  • Kasi PM, Kassi M, Khawar T. Excessive work hours of physicians in training: maladaptive coping strategies. PLoS Med. 2007 Sep;4(9):e279.
  • Saeed F, Kassi M, Ayub S, Rehman R, Kasi PM, Rizvi JH. Factors influencing medical student participation in an obstetrics and gynaecology clinic. J Pak Med Assoc. 2007 Oct;57(10):495-8.
  • Kassi M, Kasi PM. Diagnosis of cutaneous leishmaniasis by fine needle aspiration cytology: a report of 66 cases. Trop Doct. 2005 Jan;35(1):50-1.
  • Kassi M, Tareen I, Qazi A, Kasi PM. Fine-needle aspiration cytology in the diagnosis of cutaneous leishmaniasis. Ann Saudi Med. 2004 Mar-Apr; 24(2):93-7.
  • Achakzai AM, Kassi M, Kasi PM. Seroprevalence of Hepatitis B, Hepatitis C and HIV viruses in injecting drug users of Quetta, Pakistan. Tropical Doctor 2007; 37:43-45.
  • Gilani AI, Gilani UI, Kasi PM, Khan MM. Psychiatric health laws in Pakistan: from lunacy to mental health. PLoS Med. 2005 Nov;2(11):e317. Epub 2005 Sep 20.
  • Shafiq M, Tanwir M, Tariq A, Kasi PM, Zafar M et al. Epilepsy: Public knowledge and attitude in a slum area of Karachi, Pakistan. Seizure. 2007 Mar 20;
  • Umer M, Nawaz H, Kasi PM, Ahmed M, Ali SS. Outcome of triple procedure in older children with developmental dysplasia of hip (DDH). J Pak Med Assoc. 2007 Dec;57(12):591-5.
  • Kassi M, Kasi PM, Marri SM, Tareen I, Khawar T. Vector control in cutaneous leishmaniasis of the old world: A review of literature. Dermatology Online Journal 2008 June; Volume 14 (6).
  • Fatima M, Kasi PM, Rehman R, Baloch SN. Quintuplets born to a woman without fertility treatment in Pakistan. Fertil Steril. 2008 Nov;90(5):2007.e17-20.
  • Kassi M, Kassi M, Khan AK, Rehman R, Kasi PM. Marring Leishmaniasis: The stigma of Cutaneous Leishmaniasis in Pakistan and Afghanistan. PLoS Neglected Tropical Diseases PLoS Negl Trop Dis. 2008;2(10):e259. Epub 2008.
  • Fatima M, Nawaz H, Kassi M, Rehman R, Kasi PM, Kassi M, Afghan AK, Baloch SN. Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women. Singapore Med J. 2009 Jan;50(1):20-8.
  • Kasi PM, Mounzer R, Gleeson GH. Cardiovascular side effects of atomoxetine and its interactions with inhibitors of the cytochrome p450 system. Case Report Med. 2011;2011:952584. PubMed PMID: 21765848.
  • Kasi PM. Thrombotic thrombocytopenic purpura and gemcitabine. Case Rep Oncol. 2011 Jan;4(1):143-8. Epub 2011 Mar 16. PubMed PMID: 21691573; PubMed Central PMCID: PMC3114619.
  • Kasi PM, DeArmond DA. Birt-Hogg-Dubé Syndrome: Answering Questions Raised by a Case Report Published in 1962. Case Rep Oncol 2011;4:363-366.
  • Fatima M, Kasi PM, Baloch SN, Afghan AK. Experience of Emergency Peripartum Hysterectomies (EPH) at a Tertiary Care Hospital in Quetta, Pakistan. ISRN Obstetrics and Gynecology August 2011; In Press.
  • Afghan AK, Kassi M, Kasi PM, Ayub A, Kakar N, Marri SM. Clinical Manifestations and Distribution of Cutaneous Leishmaniasis in Pakistan. Accepted for Publication in Journal of Tropical Medicine. August 2011.
  • Fatima M, Kasi PM, Baloch SN, Kassi M, Marri SM, Kassi M. Incidence, Management and Outcome of Molar Pregnancies at a Tertiary Care Hospital in Quetta, Pakistan ISRN Obstetrics and Gynecology August 2011.
  • Kasi PM, Rehman R, Saeed F. Refusing male medics. studentBMJ 2007;15:169-212 May ISSN 0966-6494.
  • Achakzai M, Kasi PM. Mothers who kill their children. J Pak Psych Society. Jun 2007; 4(1):50-51.
  • Kassi M, Kasi PM, Achakzai AM. HIV in injecting drug users of Quetta, Pakistan: Reporting another outbreak. Response to article: Harm Reduct J. 2006 Aug 16;3:26.
  • Kasi PM, Naqvi H, Achakzai AM, Gilani AI et al. Offering a sustainable solution to for achieving the 'Millennium Mental Health Development Goal': The psychospiritual model. Response to this article: PLoS Med 2(10): e291.
  • Kasi PM, Kassi M. "FLAE" Approach would be unfair for the medical students. (18 January, 2007). Response to article: J PLoS Biology Vol. 5, No. 1, e18.
  • Kasi PM, Rehman R, Kassi M. Increasing Repatriation by encouraging International Liaison Programs. Response to article: PLoS Medicine Vol. 5, No. 1, e2.
  • Kasi PM. Let's not cite journals that are not open access: Countering the impact factor game. Response to article: PLoS Medicine Vol. 3, No. 6, e291
  • Waheed U, Brandt MM, Copeland CF, Field EO, Horst HM, Rubinfeld IS, Falvo AJ, Patton JH, Jordan J, Kasi PM. Optimal Glucose Control in Critically ill trauma patients. Critical Care Medicine. 34(12) Abstract supplement:A52, December 2006.
Jawad Kiani picture Jawad Kiani Primary Research Area of Interest: Cardiac resynchronization therapy (CRT).
Primary Clinical Area of Interest: Cardiology.
ISP Research Project Title: Determinants of nonresponse to CRT and mechanisms of survival benefit.
Mentor for ISP Project: Samir Saba, MD.
Publications:
  • Kiani JG, Saeed M, Parvez SH, Frossard PM. Association of G-protein beta-3 subunit gene (GNB3) T825 allele with type II diabetes. Neuro Endocrinol Lett. 2005;26(2):87-8.
  • Kiani J, Khan A, Khawar H, Shuaib F, Pervez S. Estrogen receptor alpha–negative and progesterone receptor–positive breast cancer: lab error or real entity? Pathol Oncol Res. 2006;12(4):223-7.
  • Jafary FH, Ahmed H, Kiani J. Outcomes of primary percutaneous coronary intervention at a joint commission international accredited hospital in a developing country: can good results, possibly similar to the West, be achieved? J Invasive Cardiol. 2007;19(10):417-23.
  • Kasi PM, Khawar T, Khan FH, Kiani JG, Khan UZ, Khan HM, Khuwaja UB, Rahim M. Studying the association between postgraduate trainees' work hours, stress and the use of maladaptive coping strategies. J Ayub Med Coll Abbottabad. 2007;19(3):37-41.
  • Kiani J, Imam SZ. Medicinal importance of grapefruit juice and its interaction with various drugs. Nutr J. 2007;6:33.
  • Gilani AH, Shah AJ, Zubair A, Khalid S, Kiani J, Ahmed A, Rasheed M, Ahmad VU. Chemical composition and mechanisms underlying the spasmolytic and bronchodilatory properties of the essential oil of Nepeta cataria L. J Ethnopharmacol. 2009;121(3):405-11.
  • Georgiopoulou V, Kiani J, et al. Health literacy in outpatients with heart failure: determinants and association with outcomes. Circulation. 2010;122:A21224.
  • Deka A, Kiani J, Pernetz MA, Georgiopoulou VV, Border WL, McConnell M, Lerakis S, Butler J, Martin RP, Book WM, Kalogeropoulos AP. Systemic right ventricular function and outcomes in adults with D-transposition of the great arteries with atrial switch: the value of echocardiographic quantification. J Am Coll Cardiol. 2011;57:E437 (doi:10.1016/S0735-1097(11)60437-3).
Presentations:
  • Kiani J, Sagar M, et al. HIV-1 envelope variable loops V1V5 influence on viral entry. Presented at the Research Meeting of the Partners AIDS Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, November 2005.
  • Kiani J, Frossard P, et al. Apolipoprotein B gene (Apo Xba1) is associated with essential hypertension in a Pakistani Pathan population. Presented at the Health Sciences Research Assembly, Aga Khan University, Karachi, Pakistan, March 2006.
  • Kiani J, Jafary F, et al. Survival of patients treated with primary percutaneous coronary intervention for acute myocardial infarction in a tertiary care center in Pakistan: patient characteristics and predictors of in-hospital mortality. Presented at the South Asian Association for Regional Cooperation (SAARC) Congress of Cardiology, Karachi, Pakistan, April 2006.
  • Kiani J, Gilani AH, et al. Pharmacological screening of Achilia santolina, Artemisia maritima, Nepeta cataria, Perovskia abrotanoides, and Salvia bucharica. Presented at the Research Seminar of the Committee for Young Physicians of the Association of Physicians of Pakistani-Descent of North America (APPNA) and Young Pakistani Physicians Resource Center (YPPRC), Lahore, Pakistan, December 2008.
Hrisikesh Kulkami picture Hrishikesh Kulkarni Primary Research Area of Interest: Host immune response to inflammation.
Primary Clinical Area of Interest: Pulmonary and critical care medicine and rheumatology.
ISP Research Project Title: Computerized tomography changes in patients with severe asthma.
Mentor for ISP Project: Sally Wenzel, MD.
Presentations and Publications:
  • Goenka AH, Kulkarni HS. A tribute to the indomitable spirit of Jivraj Mehta. J Postgrad Med. 2006;52(3):226-9.
  • Kulkarni HS. Second joint ICMR-CRI Indo-US workshop on research methodology: a student's perspective. J Postgrad Med. 2006;52(1):68.
  • Kulkarni HS, Dhuri SA, Uchil DA, Rege NN. Effects of ground flaxseed on diet-induced hyperlipidemia in animals. Platform presentation and third-prize travel grant at the Leiden International Medical Students' Conference, Netherlands, 2007.
  • Zinkernagel R. Science and sensibility: an interview with Professor Rolf M. Zinkernagel, Nobel Prize Winner for Medicine 1996. MedGenMed. 2007;9(4):28.
  • Kanodra NM, Jethwani KS, Kulkarni HS, Bavdekar SB, Gogtay NG. Doctors' perceptions about relicensing. J Assoc Physicians India. 2008;56:558-9. Poster presentation at the International Conference on Medical Education, Bangalore, India, 2007.
  • Gala PM, Ghorpade SA, Trivedi V, Kulkarni HS, Babar S, Kamat SK, Rege NN. Comparative evaluation of effects of ground flaxseed (Linum usitatissimum), flax oil, and atorvastatin on endothelial cell function. Presented by Gala PM at the First Asian Medical Students' Research Conference, Pune, India, 2008.
  • Goenka AH, Kulkarni HS. The laureate, the worm, and rnai: an interview with Professor Craig Mello, Nobel Prize Winner in Medicine 2006. Student BMJ. 2008;1(19):16.
  • Kulkarni HS, Kulkarni KR, Mallampalli A, Karnad DR, Parkar SR, Guntupalli KK. Comparison of anxiety, depression, and posttraumatic stress disorder in the relatives of patients in an American and Indian public hospital. Chest. 2008;134(4):100801S. Poster presentation at the Annual Meeting of the American College of Chest Physicians, Philadelphia, Pennsylvania, 2008.
  • Kulkarni HS, Ans M. Research methodology, research methods, and statistics. In: Kasi PM, ed. Research: What, Why, and How? A Treatise from Researchers to Researchers. Bloomington, IN: AuthorHouse; 2009:101-15.
  • Kulkarni HS, Joshi HI, Kothari VM, Karnad DR. Increased mean pulmonary arterial pressures are associated with a higher mortality in critically ill patients with leptospirosis. Chest. 2009;136(4):117S. Poster presentation at the Annual Meeting of the American College of Chest Physicians, San Diego, California, 2009.
  • Kulkarni HS. Less obvious predictors of post-ICU informal caregiver burden. Chest. 2010;138(4):1024.
  • Kulkarni HS, Keskar V, Bavdekar SB, Gabhale Y. Bilateral optic neuritis due to isoniazid. Indian Pediatr. 2010;47(6):533-5.
  • Shin HS, Xu F, Bagchi A, Herrup E, Valentine C, Prakash A, Kulkarni H, Wilhelmsen K, Warren HS, Hellman J. Bacterial lipoprotein Toll-like receptor 2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J Immunol. 2011;186(2):1119-30.
  • Kulkarni HS, Aggarwal R. Successful treatment of acute respiratory failure using rituximab and cyclophosphamide as a combination immunosuppressive regimen in a ventilator-dependent patient having antisynthetase syndrome. Poster presentation at the International Conference of the American Thoracic Society, Denver, Colorado, 2011.
  • Kulkarni HS, Karnad DR, Guntupalli KK. Obstetric critical care. In: Jindal SK, ed. Textbook of Pulmonary Medicine—A Developing Countries' Perspective. New Delhi, India: M/S Jaypee Brothers. In press.
  • Kulkarni HS, Guntupalli KK. Infectious complications in pregnancy. In: Vincent JL, Hall JB, eds. Encyclopedia of Intensive Care Medicine. New York, NY: Springer. In press.
Arpan Mohanty picture Arpan Mohanty Primary Research Area of Interest: Hepatitis C and other liver diseases.
Primary Clinical Area of Interest: Gastroenterology, hepatology, and infectious diseases.
ISP Research Project Title:
Mentor for ISP Project:


Entering 2009:

Ali Amjad picture Ali Amjad Primary Research Area of Interest: Recovery of immune system after stem cell transplant
Primary Clinical Area of Interest: Hematological and solid malignancies.
ISP Research Project Title: Recovery of immune system as measured by ATP release from CD4 T cells after allogeneic hematopoietic stem cell transplant.
Mentor for ISP Project: Markus Mapara, MD, PhD.
Publications:
  • Saeed SA, Ahmed S, Amjad AI, Azmatullah A, Siddique SS. A new function of human haptoglobin: endogenous inhibition of prostaglandin biosynthesis and its relation to haemoglobin binding. J Med Sci. 2003;3(5):344-57.
  • Amjad AI, Söder O, Sultana T. Testicular interleukin-1a (tIL-1a), a multifunctional cytokine with a role in testicular physiology and disease. J Coll Physicians Surg Pak. 2006;16(1):55-60.
  • Amjad AI. Clinical diagnostic reasoning and the curriculum: a medical student's perspective. Med Teach. 2008;30(4):426-7.
  • Amjad AI, Pal I. De novo primary squamous cell carcinoma of the ovary with multiple bowel metastases. J Pak Med Assoc. 2008;58(5):272-4.
  • Amjad AI, Qazi SH, Nazir Z. Enterocutaneous fistulas in children: a management challenge. J Coll Physicians Surg Pak. 2008;18(8):526-7.
  • Rauf MA, Zafar AM, Amjad AI. Comparison of different phenotypic methods of detection of methicillin resistance in Staphylococcus aureus with the molecular detection of mec-A gene. J Coll Physicians Surg Pak. 2008;18(8):529-30.
  • Parikh GC, Amjad AI, Saliba RM, et al. Autologous hematopoietic stem cell transplantation may reverse renal failure in patients with multiple myeloma. Biol Blood Marrow Transplant. 2009;15(7):812-6.
  • Qazilbash MH, Amjad AI, Qureshi S, et al. Outcome of allogeneic hematopoietic stem cell transplantation in patients with low left ventricular ejection fraction. Biol Blood Marrow Transplant. 2009;15(10):1265-70.
Presentations:
  • Outcome of allogeneic hematopoietic stem cell transplantation in patients with low left ventricular ejection fraction. Podium presentation, Resident and Fellow Section Interim Meeting, American Medical Association, Houston, Texas, November 2009.
Aju Mathew picture Aju Mathew Primary Research Area of Interest: Cardiovascular diseases, cancer, and epidemiology.
Primary Clinical Area of Interest: Hematology/oncology.
ISP Research Project Title: 1. Bisphosphonates in metastatic breast cancer
2. Triple negative breast cancer and brain metastases
Mentor for ISP Project: Dr. Adam Brufsky, MD, PhD, FACP
Publications:
  • Soman CR, Mathew A. HIV-1 prevalence in young adults in south India. Lancet. 2006;368(9530):113.
  • Seidel D, Muangpaisan W, Hiro H, Mathew A, Lyratzopoulos G. The association between body mass index and Barrett's esophagus: a systematic review. Dis Esophagus. 2009;22(7):564-70.
  • Krishnankutty RK, Mathew A, Sedimbi SK, Suryanarayan S, Sanjeevi CB. Alternative routes of insulin delivery. J Central South University. 2009;34(10):933-48.
Haq Nawaz picture Haq Nawaz Primary Research Area of Interest: Gastroenterology and hepatology.
Primary Clinical Area of Interest: Management of recurrent hepatitis C after liver transplantation.
ISP Research Project Title: Performance Characteristics of Endoscopic Ultrasound in the diagnosis of vascular invasion, lymph node metastasis and prediction of resectability of Pancreatic Cancer - A Meta-Analysis
Mentor for ISP Project: Obaid Shaikh, MD.
Publications:
  • Janjua NZ, Kasi PM, Nawaz H, Farooqui SZ, Khuwaja UB, Ul-Hassan N, Jafri SN, Lutfi SA, Kadir MM, Sathiakumar N. Acute health effects of the Tasman Spirit oil spill on residents of Karachi, Pakistan. BMC Public Health. 2006;6(1):84.
  • Khan KM, Sarfaraz N, Siddiqui S, Nawaz H. Immunohistochemical localization of G protein beta-gamma subunits in the lateral wall of the rat cochlea. J Anatomy. 2006;208(2):205-18.
  • Imam SZ, Nawaz H, Sepah YJ, Pabaney AH, Ghaffar S. Use of smokeless tobacco among groups of Pakistani medical students: a cross-sectional study. BMC Public Health. 2007;7:231.
  • Nawaz H, Imam SZ, Zubairi AB, Pabaney AH, Sepah YJ, Islam M, Khan JA. Smoking habits and beliefs of future physicians of Pakistan. Int J Tuberculosis Lung Dis. 2007;11(8):915-9.
  • Umer M, Nawaz H, Kasi PM, Ahmed M, Ali SS. Outcome of a triple procedure in older children with developmental dysplasia of the hip (DDH). J Pakistan Med Assoc. 2007;57(12):591-5.
  • Raoof M, Nawaz H, Nusrat R, Pabaney AH, Randhawa AR. Awareness and use of benzodiazepines in healthy volunteers and ambulatory patients visiting a tertiary care hospital: a cross-sectional survey. PLoS One. 2008;3(3):e1804 (doi:10.1371/journal.pone.0001804).
  • Umer M, Nawaz H. Developmental dysplasia of the hip: where do we stand? J Pakistan Med Assoc. 2008;58(1):2-4.
  • Fatima M, Nawaz H, Kassi M, Rehman R, Kasi PM, Kassi M, Afghan AK, Baloch SN. Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women. Singapore Med J. 2009;50(1):20-8.
Sumera Rizvi picture Sumera Rizvi Primary Research Area of Interest: Gastroenterology, Barrett's esophagus, pancreatic cancer, and inflammatory bowel disease.
Primary Clinical Area of Interest: Gastroenterology.
ISP Research Project Title: Biophotonics Approaches for Diagnosis and Risk Stratification of Gastrointestinal Diseases
Mentor for ISP Project: Dr. Randall Brand, Division of Gastroenterology, Hepatology & Nutrition
Publications:
  • Ilyas S, DeMars C, Buttar N. Chemoprevention in Barrett's esophagus. J Gastrointest Cancer. 2007;38(1):1-9.
  • Buttar N, DeMars C, Lomberk G, Rizvi S, Bonilla-Velez J, Achra S, Rashtak S, Wang K, Fernandez-Zapico M, Urrutia R. Dual transcription and posttranslational role of Kruppel-like factor 11 in the regulation of prostaglandin e2 biosynthesis. J Biol Chem. 2010;285(15):11433-4.


Entering 2008:

Sumera Rizvi pictureFaraz Bishehsari Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title:
Mentor for ISP Project:
Faris Khan picture Faris Khan Primary Research Area of Interest: Cardiac electrophysiology, gap junctions and arrhythmias, role of the new diagnostic markers in myocardial infarction, premature coronary artery disease and acute renal injury, and renal failure.
Primary Clinical Area of Interest: Cardiac electrophysiology.
ISP Research Project Title: The role of implantable cardioverter-defibrillators (ICDs) in patients with end-stage renal disease (ESRD) with or without dialysis.
Mentor for ISP Project: Samir Saba, MD.
Publications:
  • Khan F, Khalid I, Cheema FH. Preoperative renal function and selective renal vein renin levels as markers of favourable outcome in renovascular hypertension. J Pakistan Med Assoc. 2007;57(11):575.
  • Kiryluk K, Khan F, Valeri AM. Acute chorea due to a basal ganglia process in a hemodialysis patient. Kidney Int. 2008;73(9):1087-91.
  • Nickolas TL, O'Rourke MJ, Yang J, Sise ME, Canetta PA, Barasch N, Buchen C, Khan F, Mori K, Giglio J, Devarajan P, Barasch J. Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase–associated lipocalin for diagnosing acute kidney injury. Ann Intern Med. 2008;148(11):810-9.
  • Khan F, Rahman W, Cheema FH. Cells, adult. In: Svendsen C, Ebert A, eds. Encyclopedia of Stem Cell Research. Thousand Oaks, CA: Sage; 2008:69-70.
  • Khan F, Rahman W, Farid N. Cells, embryonic. In: Svendsen C, Ebert A, eds. Encyclopedia of Stem Cell Research. Thousand Oaks, CA: Sage; 2008:75-6.
  • Rahman W, Khan F, Cheema FH. Cells, mouse. In: Svendsen C, Ebert A, eds. Encyclopedia of Stem Cell Research. Thousand Oaks, CA: Sage; 2008:81-3.
  • Rahman W, Khan F, Malik N. Cells, monkey. In: Svendsen C, Ebert A, eds. Encyclopedia of Stem Cell Research. Thousand Oaks, CA: Sage; 2008:80-1.
  • Khan F, Malik N, Cheema FH. Cells, sources of. In: Svendsen C, Ebert A, eds. Encyclopedia of Stem Cell Research. Thousand Oaks, CA: Sage; 2008:85-8.
  • Mamoona F, Rao MZ, Khan F, Cheema FH. Renal stem cells. In: Svendsen C, Ebert A, eds. Encyclopedia of Stem Cell Research. Thousand Oaks, CA: Sage; 2008:470-2.
  • Khan F, Adelstein E, Saba S. Implantable cardioverter-defibrillators confer survival benefit in patients with renal insufficiency but not in dialysis-dependent patients. J Interventions Cardiac Electrophysiol. 2010;28(2):117-23.
Rawad Mounzer picture Rawad Mounzer Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title:
Mentor for ISP Project:
Mansoor Tanwir picture Mansoor Tanwir Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title:
Mentor for ISP Project:


Entering 2007:

Jana Al Hashash picture
Jana Al Hashash		 Primary Research Area of Interest: Colorectal cancers, inflammatory bowel disease, and functional dyspepsia.
Primary Clinical Area of Interest: Gastroenterology.
ISP Research Project Title: Role of tertiary lymphoid organs in chronic allograft rejection.
Mentor for ISP Project: Faddi Lakkis, MD.
Presentations:
  • Hashash JG, Skoury A, Aoun N, Shamseddeen W, Barada K. Gross lower-gastrointestinal bleeding in patients on anticoagulant and/or antiplatelet therapy: endoscopic findings and clinical outcomes. Gastroenterology. 2007;32(Suppl 2):A195-6. Poster presentation at Digestive Disease Week, Washington, DC, May 2007.
  • Abdul-Baki H, Hashash JG, El Hajj II, Azar C, El Zahabi L, Mourad FH, Barada KA, Sharara AI. A randomized controlled double-blind trial of the adjunct use of tegaserod in whole- or split-dose PEG-electrolyte solution for colonoscopy preparation. Endoscopy. 2007;39(Suppl 1):A362. Poster presentation at the 15th United European Gastroenterology Week, Paris, October 2007.
  • Hashash JG, Abdul-Baki H, Azar C, El Hajj II, El Zahabi L, Chaar H, Sharara AI. A randomized double-blind placebo-controlled cross-over study of flupenthixol and melitracen in functional dyspepsia. Gut. 2007;56(Suppl 3):A8. Oral presentation at the 15th United European Gastroenterology Week, Paris, October 2007. [Winner of the Junior Investigator Award.]
  • Hashash JG, Skoury A, Haddad R, El-Samad S, Soweid A. A randomized open-label trial of on-demand use of rabeprazole vs. ranitidine in patients with non-erosive reflux disease. Gut. 2007;56(Suppl 3):A215. Poster presentation at the 15th United European Gastroenterology Week, Paris, October 2007.
  • Sharara AI, El Hajj I, Maasri K, Hashash JG, Araj GF. The effect of acid, pepsin, and gastric juice on the in vitro growth and sporulation of Clostridium difficile. Poster presentation at Digestive Disease Week, San Diego, California, May 2008.
Publications:
  • Azar C, Soweid A, Berro Z, Salem ZM, Geara FB, Kattar MM, Hashash JG, Barada KA. Duodenal mucosa-associated lymphoid tissue lymphoma successfully treated by radiation therapy. Clin Lymphoma Myeloma. 2007;7:428-31.
  • El Hajj I, Hashash JG, Kfoury Baz E, Abdul-Baki H, Sharara AI. ABO blood group and gastric cancer: rekindling an old fire? South Med J. 2007;100:726-7.
  • Hashash JG, Atweh LA, Saliba T, Chakhachiro Z, Al-Kutoubi A, Tawil A, Barada K. Acute NSAID-induced transmural duodenitis and extensive duodenal ulceration: a case report. Clin Therapeutics. 2007;29:2448-52.
  • Kairouz S, Hashash J, Kabbara W, McHayleh W, Tabbara IA. Dendritic cell neoplasms: an overview. Am J Hematol. 2007;82:924-8.
  • Abdul-Baki H, Hashash JG, El Hajj II, Azar C, El Zahabi L, Mourad FH, Barada KA, Sharara AI. A randomized controlled double-blind trial of the adjunct use of tegaserod in whole-dose or split-dose polyethylene glycol electrolyte solution for colonoscopy preparation. Gastrointestinal Endoscopy. 2008;68:294-300.
  • Hashash JG, Abdul-Baki H, Azar C, El Hajj II, El Zahabi L, Chaar H, Sharara AI. A randomized double-blind placebo-controlled cross-over study of flupenthixol and melitracen in functional dyspepsia. Aliment Pharmacol Therapeutics. 2008;27:1148-55.
  • Barada K, Abdul-Baki H, El Hajj II, Hashash JG, Green PH. Gastrointestinal bleeding in the setting of anticoagulation and antiplatelet therapy. J Clin Gastroenterol. 2009;43:5-12.
  • Hashash JG, Shamseddeen W, Skoury A, Aoun N, Barada K. Gross lower gastrointestinal bleeding in patients on anticoagulant and/or antiplatelet therapy: endoscopic findings, management, and clinical outcomes. J Clin Gastroenterol. 2009;43:36-42.
  • Pollack SM, O'Connor TP Jr, Hashash J, Tabbara IA. Nonmyeloablative therapy and reduced-intensity conditioning for allogeneic hematopoietic stem cell transplantation: a clinical review. Am J Clin Oncol. 2009;32:618-28.
Breno da Rocha Lima picture Breno da Rocha Lima Primary Research Area of Interest: Osteoporosis and glaucoma.
Primary Clinical Area of Interest: Endocrinology and ophthalmology.
ISP Research Project Title: High-resolution magnetic resonance imaging (MRI) of the wrist: a novel technique to examine skeletal integrity in men with prostate cancer.
Mentor for ISP Project: Susan Greenspan, MD.
Presentations:
  • da Rocha Lima B, Venzara F, de los Santos R, Ventura L, Porciatti V. Postural changes of intraocular pressure and their impact on retinal ganglion cell function. Presentation at the Annual Meeting of the Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, May 2007.
  • Ventura L, da Rocha Lima B, Venzara F, Porciatti V. Postural changes of intraocular pressure and their impact on retinal ganglion cell function. Presentation at the Seventh Biannual Meeting of the North American Perimetric Society, Skaneateles, New York, September 2007.
Nikhil Gupta picture Nikhil Gupta Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title: Effect of small bowel transplant on the bone mass of recipients.
Mentor for ISP Project: Susan Greenspan, MD.
Hussain Mahmud picture
Hussain Mahmud		 Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title:
Mentor for ISP Project:


Entering 2006:

Walid El Ayass picture
Walid El Ayass		 Primary Research Area of Interest: Predictors of bone metastasis progression in patients with breast cancer.
Primary Clinical Area of Interest: Hematology/oncology. 
ISP Research Project Title: Predictors of bone metastasis progression in patients with breast cancer.
Mentor for ISP Project: Adam Brufsky, MD, PhD.
Postresidency Plans: Hematology/oncology fellowship, George Washington University.
Gaurav Gupta picture
Gaurav Gupta		 Primary Research Area of Interest: Renal transplantation and BK virus allograft nephropathy.
Primary Clinical Area of Interest: Nephrology and kidney transplantation.
ISP Research Project Title: Causes of renal allograft failure and their impact on postgraft survival.
Mentor for ISP Project: Parmjeet Randhawa, MD.
Presentations:
  • Gupta G, Gasper G, Bista B, Shapiro R, Randhawa P, Vats A. High production of TGF-ß increases the risk of development of BK virus allograft nephropathy. Oral presentation at the World Transplant Congress, Boston, Massachusetts, July 2006.
  • Gupta G, Jahnukainen T, Ishwad C, Gasper G, Kwak J, Choi M, Randhawa P, Vats A. BK virus upregulates TGF-ß as well as specific components of the TGF-ß signaling pathway. Oral presentation at the World Transplant Congress, Boston, Massachusetts, July 2006.
  • Gupta G, Shapiro R, Basu A, Tan H, Morgan C, Vats A, Randhawa R. BK viremia without demonstrated nephropathy in kidney transplant patients receiving Campath induction and steroid avoidance. Presentation at the Fourth International Conference on Polyomaviruses, Barcelona, Spain, October 2007.
  • Gupta G, Shapiro R, Morgan C, Basu A, Tan H, Randhawa P. Neutrophilic tubulitis as a marker for urinary tract infection in C4d-positive renal allograft biopsies. Presentation at the American Transplant Congress, Toronto, Ontario, Canada, June 2008.
Publications:
  • Gupta G, Shapiro R, Randhawa P, Vats A. Low incidence of BK virus nephropathy after simultaneous kidney pancreas transplantation. Transplantation. 2006;82:382-8.
  • Jahnukainen T, Malehorn D, Sun M, Lyons-Weiler J, Bigbee W, Gupta G, Shapiro R, Randhawa P, Pelikan R, Hauskrecht M, Vats A. Proteomic analysis of urine in kidney transplant patients with BK virus nephropathy. J Am Soc Nephrol. 2006;17:3248-56.
  • Randhawa P, Gupta G, Vats A, Shapiro R, Viscidi RP. Immunoglobulin G, A, and M responses to BK virus in renal transplantation. Clin Vaccine Immunol. 2006;13:1057-63.
  • Sharma P, Gupta G, Vats A, Shapiro R, Randhawa P. Phylogenetic analysis of polyomavirus BK sequences. J Virol. 2006;80:8869-79.
  • Bista BR, Ishwad C, Wadowsky RM, Manna P, Randhawa PS, Gupta G, Adhikari M, Tyagi R, Gasper G, Vats A. Development of a loop-mediated isothermal amplification assay for rapid detection of BK virus. J Clin Microbiol. 2007;45:1581-7.
  • Sharma PM, Gupta G, Vats A, Shapiro R, Randhawa PS. Polyomavirus BK noncoding control region rearrangements in health and disease. J Med Virol. 2007;79:1199-207.
Arslan Kahloon picture
Arslan Kahloon		 Primary Research Area of Interest: Viral hepatitis and ulcerative colitis.
Primary Clinical Area of Interest: Gastroenterology and hepatology.
ISP Research Project Title: Surveillance colonoscopy underestimates dysplasia in patients with ulcerative colitis.
Mentor for ISP Project: Miguel Regueiro, MD, and Obaid Shaikh, MD.
Postresidency Plans: Gastroenterology fellowship, Indiana University.
Saurabh Malhotra picture
Saurabh Malhotra		 Primary Research Area of Interest: Vulnerable atherosclerotic plaques and cardiovascular epidemiology.
Primary Clinical Area of Interest: Cardiovascular imaging.
ISP Research Project Title: Predictors of electrocardiographic changes during myocardial perfusion imaging.
Mentor for ISP Project: Prem Soman, MD, PhD, MRCP.
Postresidency Plans: Cardiovascular disease fellowship, Indiana University.
Presentations:
  • Malhotra S, Lai S, Tandri H, Castillo E, Szarf G, Wasserman BA. Improved reliability of magnetic resonance imaging (MRI) measurements of carotid artery wall thickness with contrast enhancement. Presentation at the Meeting of the North American Society of Cardiac Imaging, Las Vegas, Nevada, October 2006.
  • Ezeokoli C, Malhotra S, Astor B, Steinman D, Wasserman BA. Retropharyngeal carotid artery: a cautionary tale. Presentation at the Annual Meeting of the American Society of Neuroradiology, Chicago, Illinois, June 2007.
  • Dasari A, Malhotra S, Spagnoletti CL. A rare complication of a common disease: pyogenic liver abscess due to diverticulitis. Presentation at the Annual Meeting of the Society of General Internal Medicine, Pittsburgh, Pennsylvania, April 2008.
  • Dasari A, Malhotra S, Spagnoletti CL. Sore throat: not always the usual suspects. Presentation at the Annual Meeting of the Society of General Internal Medicine, Pittsburgh, Pennsylvania, April 2008.
  • Malhotra S, Lertratanakul A, Dasari A, Spagnoletti CL. An unusual cause for low back pain: mycotic abdominal aortic aneurysm. Presentation at the Annual Meeting of the Society of General Internal Medicine, Pittsburgh, Pennsylvania, April 2008.
  • Malhotra S, Follansbee WP, Soman P. Ischemic electrocardiographic response to exercise is more strongly associated with the severity than the extent of single photon emission computed tomography (SPECT) ischemia. Presentation at the Meeting of the American Society of Nuclear Cardiology, Boston, Massachusetts, September 2008.
  • Malhotra S, Follansbee WP, Soman P. Ischemic electrocardiographic response to exercise is more strongly associated with the severity than the extent of SPECT ischemia in individuals with significant coronary artery disease. Presentation at the Meeting of the American Heart Association, New Orleans, Louisiana, November 2008.
Publications:
  • Guallar E, Silbergeld EK, Navas-Acien A, Malhotra S, Astor BC, Sharrett R, Schwartz BS. Confounding of the relation between homocysteine and peripheral arterial disease by lead, cadmium, and renal function. Am J Epidemiol. 2006;163:700-8.
  • Gupta P, Malhotra S, Singh DK, Dua T. Length of postnatal stay in healthy newborns and rehospitalization following their early discharge. Indian J Pediatr. 2006;73:897-900.
  • Golden SH, Malhotra S, Wand GS, Brancati FL, Ford D, Horton K. Adrenal gland volume and dexamethasone-suppressed cortisol correlate with total daily salivary cortisol in African-American women. J Clin Endocrinol Metab. 2007;92:1358-63.
John Nasr picture
John Nasr		 Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title:
Mentor for ISP Project:
Selahattin Turen picture
Selahattin Turen		 Primary Research Area of Interest: ADP receptor gene polymorphism and clopidogrel resistance.
Primary Clinical Area of Interest: Cardiology.
ISP Research Project Title: Serum lactate dehydrogenase (LDH) level is a prognostic factor in patients who have locoregionally advanced nasopharyngeal carcinoma and are treated with chemoradiotherapy.
Mentor for ISP Project: Oscar Marroquin, MD.
Presentations:
  • Turen S, Ozyar E, Altundag MK, Gullu I. Serum LDH level is a prognostic factor in locoregionally advanced nasopharyngeal carcinoma (NPC) patients treated with chemotherapy. Lung Cancer. 2004;46(Suppl 1):S82. Poster presentation at the Third International Chicago Symposium on Malignancies of the Chest and Head and Neck, Chicago, Illinois, October 2004.
Publications:
  • Altundag K, Altundag O, Akyurek S, Karakaya E, Turen S. Inactivation of E-cadherin and less sensitivity of lobular breast carcinoma cells to chemotherapy [letter]. Breast. 2006;15:300.
  • Turen S, Ozyar E, Altundag K, Gullu I, Atahan IL. Serum lactate dehydrogenase level is a prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy. Cancer Investigation. 2007;25:315-21.


Entering 2005:

Adam Giermasz picture
Adam Giermasz		 Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title:
Mentor for ISP Project:
Angela Huang picture
Angela Huang		 Primary Research Area of Interest: Cardiovascular preventive medicine.
Primary Clinical Area of Interest: General medicine.
ISP Research Project Title: Awareness, accuracy, and predictive validity of self-reported cholesterol levels in women.
Mentor for ISP Project: Robert Glynn, ScD.
Postresidency Plans: Hospitalist.
Publications:
  • Huang PY, Buring JE, Ridker PM, Glynn RJ. Awareness, accuracy, and predictive validity of self-reported cholesterol in women. J Gen Intern Med. 2007;22:606-13.
Ariel Lopez picture
Ariel Lopez		 Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title: Evidence of Vegf downregulation in carcinogen-induced lung tumors from transgenic mice overexpressing human hepatocyte growth factor (HGF) in the small airways.
Mentor for ISP Project: Jill Siegfried, PhD.
Ali Masud picture
Ali Masud		 Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title: Stress-induced death of endoplasmic reticulum requires the intrinsic pathway of apoptosis.
Mentor for ISP Project:
Jamal Rana picture
Jamal Rana		 Primary Research Area of Interest:
Primary Clinical Area of Interest:
ISP Research Project Title: The role of obesity versus physical activity in predicting coronary heart disease. The association of C-reactive protein with obesity versus physical activity: the EPIC-Norfolk Prospective Population Study.
Mentor for ISP Project: